Home
Browse
Download
About
Data Sources

ScerTF

Details for MOT3

The Table below describes all of the matrices annotated to MOT3 in this database. For each individual matrix, we provide several metrics related to the performance of that matrix in accurately representing the DNA binding specificity of the annotated transcription factor. The Fisher's p-value represents the probability that the recommended matrix identified MOT3-bound promoters by random chance. If no experimental data exists for this particular TF, the field is labeled as "No Data". In addition to benchmarking against high-throughput experimental data, we also inform our recommendations based on matrix information content, length, and corroboration by experimental studies of individual of cis-regulatory sequences.

Each individual matrix can be downloaded as a position count matrix (PCM), position frequency matrix (PFM), or position weight matrix (PWM). Click on the appropriate button in the left column to download the desired matrix.

Also provided is a recommended cutoff to use when scanning a genome for regulatory sequences with the provided position weight matrix. An optimal cutoff was identified for each position weight matrix that provides the greatest discriminative power to distinguish between bound and unbound sequences in available ChIP experiments.

Recommended Matrix:
For information about selection criteria click here

Source

Logo

Detailed Information

MOT3

Matrices:




Data Source:
Macisaac et. al
Fisher's P-value
0.0012


Information Content
8.274

Max PWM Score
7.16

Recommended PWM Cutoff
7.16
Recommended Position Specific Matrix for MOT3 comes from Macisaac et. al
 
MOT3: Nuclear transcription factor with two Cys2-His2 zinc fingers; involved in repression of a subset of hypoxic genes by Rox1p, repression of several DAN/TIR genes during aerobic growth, and repression of ergosterol biosynthetic genes
Aliases: YMR070W, ROX7
Genes Bound in MOT3 ChIP-chip: YAL004W, YAL059W, YAR047C, YAR073W, YAR075W, YBL020W, YBL021C, YBL022C, YBL029W, YBR012C, YBR012W-A, YBR012W-B, YBR013C, YBR032W, YBR056W, YBR083W, YBR089C-A, YBR090C +45 more
Genes affected by MOT3 deletion: YCL055W, YHL044W, YIL080W, YAL068C, YDL131W, YGL039W, YGL009C, YFR036W, YLR056W, YLR461W, YLR432W, YOR065W, YPL049C, YIL082W, YJR047C, YLR219W, YMR013C +146 more
TF-TF interactions for MOT3: None
*Important: MOT3 is not known to be a sequence-specific DNA binding protein. However, it may complex with other TFs. Please visit SGD for more information.


Additional Candidate Matrices:
Source
Logo
Detailed Information
MOT3_C

Matrices:




Data Source:
Foat et. al.
Fisher's P-value
0.0010


Information Content
10.017

Max PWM Score
9.34

Recommended PWM Cutoff
8.86
MOT3

Matrices:




Data Source:
Harbison et. al.
Fisher's P-value
0.0012


Information Content
8.282

Max PWM Score
7.16

Recommended PWM Cutoff
7.16
MOT3_B

Matrices:




Data Source:
Foat et. al.
Fisher's P-value
0.0055


Information Content
16.335

Max PWM Score
15.73

Recommended PWM Cutoff
9.12
MOT3_A

Matrices:




Data Source:
Foat et. al.
Fisher's P-value
0.4861


Information Content
17.473

Max PWM Score
18.78

Recommended PWM Cutoff
11.7
MOT3_D

Matrices:




Data Source:
Foat et. al.
Fisher's P-value
1.0000


Information Content
19.445

Max PWM Score
21.78

Recommended PWM Cutoff
16.34