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ScerTF

Details for FZF1

The Table below describes all of the matrices annotated to FZF1 in this database. For each individual matrix, we provide several metrics related to the performance of that matrix in accurately representing the DNA binding specificity of the annotated transcription factor. The Fisher's p-value represents the probability that the recommended matrix identified FZF1-bound promoters by random chance. If no experimental data exists for this particular TF, the field is labeled as "No Data". In addition to benchmarking against high-throughput experimental data, we also inform our recommendations based on matrix information content, length, and corroboration by experimental studies of individual of cis-regulatory sequences.

Each individual matrix can be downloaded as a position count matrix (PCM), position frequency matrix (PFM), or position weight matrix (PWM). Click on the appropriate button in the left column to download the desired matrix.

Also provided is a recommended cutoff to use when scanning a genome for regulatory sequences with the provided position weight matrix. An optimal cutoff was identified for each position weight matrix that provides the greatest discriminative power to distinguish between bound and unbound sequences in available ChIP experiments.

Recommended Matrix:
For information about selection criteria click here

Source

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Detailed Information

FZF1

Matrices:




Data Source:
Badis et. al.
Fisher's P-value
0.6524


Information Content
10.105

Max PWM Score
7.8

Recommended PWM Cutoff
7.8
Recommended Position Specific Matrix for FZF1 comes from Badis et. al.
 
FZF1: Transcription factor involved in sulfite metabolism, sole identified regulatory target is SSU1, overexpression suppresses sulfite-sensitivity of many unrelated mutants due to hyperactivation of SSU1, contains five zinc fingers
Aliases: YGL254W, SUL1, RSU1, NRC299
Genes Bound in FZF1 ChIP-chip: YAL017W, YAL018C, YAL022C, YBL001C, YBR012C, YBR013C, YBR040W, YBR154C, YBR155W, YBR160W, YBR178W, YBR188C, YBR189W, YCL039W, YCL041C, YCL043C, YDL045W-A, YDL089W +79 more
Genes affected by FZF1 deletion: YIL082W-A, YHR146W, YMR220W, YBR093C, YBR129C, YER029C, YOR229W, YOR073W, YOR075W, YGL212W, YNL090W, YOR074C, YMR145C, YPL092W, YPL156C, YMR144W, YNL154C +12 more
TF-TF interactions for FZF1: SPT23
Click here to see target gene co-expression data supporting TF-TF interaction predictions


Additional Candidate Matrices:
Source
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Detailed Information
FZF1

Matrices:




Data Source:
Foat et. al.
Fisher's P-value
1.0000


Information Content
19.470

Max PWM Score
18.77

Recommended PWM Cutoff
14.08