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ScerTF

Details for MATA1

The Table below describes all of the matrices annotated to MATA1 in this database. For each individual matrix, we provide several metrics related to the performance of that matrix in accurately representing the DNA binding specificity of the annotated transcription factor. The Fisher's p-value represents the probability that the recommended matrix identified MATA1-bound promoters by random chance. If no experimental data exists for this particular TF, the field is labeled as "No Data". In addition to benchmarking against high-throughput experimental data, we also inform our recommendations based on matrix information content, length, and corroboration by experimental studies of individual of cis-regulatory sequences.

Each individual matrix can be downloaded as a position count matrix (PCM), position frequency matrix (PFM), or position weight matrix (PWM). Click on the appropriate button in the left column to download the desired matrix.

Also provided is a recommended cutoff to use when scanning a genome for regulatory sequences with the provided position weight matrix. An optimal cutoff was identified for each position weight matrix that provides the greatest discriminative power to distinguish between bound and unbound sequences in available ChIP experiments.

Recommended Matrix:
For information about selection criteria click here

Source

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Detailed Information

MATA1

Matrices:




Data Source:
Macisaac et. al
Fisher's P-value
0.0005


Information Content
10.775

Max PWM Score
8.76

Recommended PWM Cutoff
8.76
Recommended Position Specific Matrix for MATA1 comes from Macisaac et. al
 
MATA1: Expressed copy (at MATa) of a1; homeobox-domain protein that, along with alpha2, represses transcription of haploid-specific genes in diploid cells; a1 sequence is not present in SGD because the sequenced S288C strain is MATalpha, not MATa
Aliases: MATA1, A1
Genes Bound in MATA1 ChIP-chip: YBL018C, YBR098W, YBR100W, YBR102C, YBR103W, YBR281C, YBR282W, YCR083W, YDL192W, YDR066C, YDR177W, YDR235W, YDR365C, YDR365W-A, YDR365W-B, YDR367W, YDR372C, YDR373W +61 more
Genes affected by MATA1 deletion: No Data
TF-TF interactions for MATA1: None
*Important: MATA1 is not known to be a sequence-specific DNA binding protein. However, it may complex with other TFs. Please visit SGD for more information.


Additional Candidate Matrices:
Source
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Detailed Information
MATA1

Matrices:




Data Source:
Foat et. al.
Fisher's P-value
2.50e-07


Information Content
18.124

Max PWM Score
17.54

Recommended PWM Cutoff
10.95