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ScerTF

ScerTF

The table below describes all of the transcription factors curated in the database. The position specific matrix provided for each TF has been selected as the best available representation of the DNA binding specificity for that transcription factor. For information about selection criteria click here.

For performance benchmarks of all the matrices annotated to particular transcription factor, click on the name of that transcription factor in the left column or simply click on the TF logo.

TF
Matrix Information
ABF1
Recommended Position Specific Matrix for ABF1 comes from Macisaac et. al

ABF1: DNA binding protein with possible chromatin-reorganizing activity involved in transcriptional activation, gene silencing, and DNA replication and repair
Aliases: YKL112W, SBF1, REB2, OBF1, BAF1
For More information on ABF1 visit SGD
ABF2
Recommended Position Specific Matrix for ABF2 comes from Badis et. al.

ABF2: Mitochondrial DNA-binding protein involved in mitochondrial DNA replication and recombination, member of HMG1 DNA-binding protein family; activity may be regulated by protein kinase A phosphorylation
Aliases: YMR072W
For More information on ABF2 visit SGD
ACA1
Recommended Position Specific Matrix for ACA1 comes from Foat et. al.

ACA1: Basic leucine zipper (bZIP) transcription factor of the ATF/CREB family, may regulate transcription of genes involved in utilization of non-optimal carbon sources
Aliases: YER045C
For More information on ACA1 visit SGD
ACE2
Recommended Position Specific Matrix for ACE2 comes from Macisaac et. al

ACE2: Transcription factor that activates expression of early G1-specific genes, localizes to daughter cell nuclei after cytokinesis and delays G1 progression in daughters, localization is regulated by phosphorylation; potential Cdc28p substrate
Aliases: YLR131C
For More information on ACE2 visit SGD
ADR1
Recommended Position Specific Matrix for ADR1 comes from Foat et. al.

ADR1: Carbon source-responsive zinc-finger transcription factor, required for transcription of the glucose-repressed gene ADH2, of peroxisomal protein genes, and of genes required for ethanol, glycerol, and fatty acid utilization
Aliases: YDR216W
For More information on ADR1 visit SGD
AFT1
Recommended Position Specific Matrix for AFT1 comes from Foat et. al.

AFT1: Transcription factor involved in iron utilization and homeostasis; binds the consensus site PyPuCACCCPu and activates the expression of target genes in response to changes in iron availability
Aliases: YGL071W, RCS1
For More information on AFT1 visit SGD
AFT2
Recommended Position Specific Matrix for AFT2 comes from Fordyce et. al.

AFT2: Iron-regulated transcriptional activator; activates genes involved in intracellular iron use and required for iron homeostasis and resistance to oxidative stress; similar to Aft1p
Aliases: YPL202C
For More information on AFT2 visit SGD
ARG80
Recommended Position Specific Matrix for ARG80 comes from Morozov et. al.

ARG80: Transcription factor involved in regulation of arginine-responsive genes; acts with Arg81p and Arg82p
Aliases: YMR042W, ARGRI, ARGR1
For More information on ARG80 visit SGD
ARG81
Recommended Position Specific Matrix for ARG81 comes from Macisaac et. al

ARG81: Zinc-finger transcription factor of the Zn(2)-Cys(6) binuclear cluster domain type, involved in the regulation of arginine-responsive genes; acts with Arg80p and Arg82p
Aliases: YML099C, ARGRII, ARGR2
For More information on ARG81 visit SGD
ARO80
Recommended Position Specific Matrix for ARO80 comes from Morozov et. al.

ARO80: Zinc finger transcriptional activator of the Zn2Cys6 family; activates transcription of aromatic amino acid catabolic genes in the presence of aromatic amino acids
Aliases: YDR421W
For More information on ARO80 visit SGD
ARR1
Recommended Position Specific Matrix for ARR1 comes from Morozov et. al.

ARR1: Transcriptional activator of the basic leucine zipper (bZIP) family, required for transcription of genes involved in resistance to arsenic compounds
Aliases: YPR199C, ACR1, YAP8
For More information on ARR1 visit SGD
ASG1
Recommended Position Specific Matrix for ASG1 comes from Zhu et. al.

ASG1: Zinc cluster protein proposed to function as a transcriptional regulator involved in the stress response; null mutants have a respiratory deficiency, calcofluor white sensitivity and slightly increased cycloheximide resistance
Aliases: YIL130W
For More information on ASG1 visit SGD
ASH1
Recommended Position Specific Matrix for ASH1 comes from Macisaac et. al

ASH1: Zinc-finger inhibitor of HO transcription; mRNA is localized and translated in the distal tip of anaphase cells, resulting in accumulation of Ash1p in daughter cell nuclei and inhibition of HO expression; potential Cdc28p substrate
Aliases: YKL185W
For More information on ASH1 visit SGD
AZF1
Recommended Position Specific Matrix for AZF1 comes from Macisaac et. al

AZF1: Zinc-finger transcription factor, involved in induction of CLN3 transcription in response to glucose; genetic and physical interactions indicate a possible role in mitochondrial transcription or genome maintenance
Aliases: YOR113W
For More information on AZF1 visit SGD
BAS1
Recommended Position Specific Matrix for BAS1 comes from Aligned Matrix

BAS1: Myb-related transcription factor involved in regulating basal and induced expression of genes of the purine and histidine biosynthesis pathways; also involved in regulation of meiotic recombination at specific genes
Aliases: YKR099W
For More information on BAS1 visit SGD
CAD1
Recommended Position Specific Matrix for CAD1 comes from Aligned Matrix

CAD1: AP-1-like basic leucine zipper (bZIP) transcriptional activator involved in stress responses, iron metabolism, and pleiotropic drug resistance; controls a set of genes involved in stabilizing proteins; binds consensus sequence TTACTAA
Aliases: YDR423C, YAP2
For More information on CAD1 visit SGD
CAT8
Recommended Position Specific Matrix for CAT8 comes from Badis et. al.

CAT8: Zinc cluster transcriptional activator necessary for derepression of a variety of genes under non-fermentative growth conditions, active after diauxic shift, binds carbon source responsive elements
Aliases: YMR280C, MSP8, DIL1
For More information on CAT8 visit SGD
CBF1
Recommended Position Specific Matrix for CBF1 comes from Macisaac et. al

CBF1: Helix-loop-helix protein that binds the motif CACRTG, which is present at several sites including MET gene promoters and centromere DNA element I (CDEI); required for nucleosome positioning at this motif; targets Isw1p to DNA
Aliases: YJR060W, CPF1, CEP1
For More information on CBF1 visit SGD
CEP3
Recommended Position Specific Matrix for CEP3 comes from Zhu et. al.

CEP3: Essential kinetochore protein, component of the CBF3 complex that binds the CDEIII region of the centromere; contains an N-terminal Zn2Cys6 type zinc finger domain, a C-terminal acidic domain, and a putative coiled coil dimerization domain
Aliases: YMR168C, CSL1, CBF3B, CBF3
For More information on CEP3 visit SGD
CHA4
Recommended Position Specific Matrix for CHA4 comes from Morozov et. al.

CHA4: DNA binding transcriptional activator, mediates serine/threonine activation of the catabolic L-serine (L-threonine) deaminase (CHA1); Zinc-finger protein with Zn[2]-Cys[6] fungal-type binuclear cluster domain
Aliases: YLR098C, SIL3, SIL2
For More information on CHA4 visit SGD
CIN5
Recommended Position Specific Matrix for CIN5 comes from Aligned Matrix

CIN5: Basic leucine zipper (bZIP) transcription factor of the yAP-1 family, mediates pleiotropic drug resistance and salt tolerance; nuclearly localized under oxidative stress and sequestered in the cytoplasm by Lot6p under reducing conditions
Aliases: YOR028C, YAP4, HAL6
For More information on CIN5 visit SGD
CRZ1
Recommended Position Specific Matrix for CRZ1 comes from Aligned Matrix

CRZ1: Transcription factor that activates transcription of genes involved in stress response; nuclear localization is positively regulated by calcineurin-mediated dephosphorylation
Aliases: YNL027W, TCN1, HAL8
For More information on CRZ1 visit SGD
CST6
Recommended Position Specific Matrix for CST6 comes from Badis et. al.

CST6: Basic leucine zipper (bZIP) transcription factor of the ATF/CREB family, proposed to be a regulator of oleate responsive genes; involved in utilization of non-optimal carbon sources and chromosome stability
Aliases: YIL036W, SHF1, ACA2
For More information on CST6 visit SGD
CUP2
Recommended Position Specific Matrix for CUP2 comes from Pachkov et al

CUP2: Copper-binding transcription factor; activates transcription of the metallothionein genes CUP1-1 and CUP1-2 in response to elevated copper concentrations
Aliases: YGL166W, ACE1
For More information on CUP2 visit SGD
CUP9
Recommended Position Specific Matrix for CUP9 comes from Morozov et. al.

CUP9: Homeodomain-containing transcriptional repressor of PTR2, which encodes a major peptide transporter; imported peptides activate ubiquitin-dependent proteolysis, resulting in degradation of Cup9p and de-repression of PTR2 transcription
Aliases: YPL177C
For More information on CUP9 visit SGD
DAL80
Recommended Position Specific Matrix for DAL80 comes from Harbison et. al.

DAL80: Negative regulator of genes in multiple nitrogen degradation pathways; expression is regulated by nitrogen levels and by Gln3p; member of the GATA-binding family, forms homodimers and heterodimers with Deh1p
Aliases: YKR034W, UGA43
For More information on DAL80 visit SGD
DAL81
Recommended Position Specific Matrix for DAL81 comes from Foat et. al.

DAL81: Positive regulator of genes in multiple nitrogen degradation pathways; contains DNA binding domain but does not appear to bind the dodecanucleotide sequence present in the promoter region of many genes involved in allantoin catabolism
Aliases: YIR023W, UGA35
For More information on DAL81 visit SGD
DAL82
Recommended Position Specific Matrix for DAL82 comes from Foat et. al.

DAL82: Positive regulator of allophanate inducible genes; binds a dodecanucleotide sequence upstream of all genes that are induced by allophanate; contains an UISALL DNA-binding, a transcriptional activation, and a coiled-coil domain
Aliases: YNL314W
For More information on DAL82 visit SGD
DIG1
Recommended Position Specific Matrix for DIG1 comes from Foat et. al.

DIG1: Regulatory protein of unknown function, constitutively-expressed, involved in the regulation of mating-specific genes and the invasive growth pathway, required for MAP-kinase imposed repression, inhibits pheromone-responsive transcription
Aliases: YPL049C, RST1
For More information on DIG1 visit SGD
DOT6
Recommended Position Specific Matrix for DOT6 comes from Zhu et. al.

DOT6: Protein involved in rRNA and ribosome biogenesis; binds polymerase A and C motif; subunit of the RPD3L histone deacetylase complex; similar to Tod6p; has chromatin specific SANT domain; involved in telomeric gene silencing and filamentation
Aliases: YER088C, PBF2
For More information on DOT6 visit SGD
ECM22
Recommended Position Specific Matrix for ECM22 comes from Zhu et. al.

ECM22: Sterol regulatory element binding protein, regulates transcription of sterol biosynthetic genes; contains Zn[2]-Cys[6] binuclear cluster; homologous to Upc2p; relocates from intracellular membranes to perinuclear foci on sterol depletion
Aliases: YLR228C
For More information on ECM22 visit SGD
ECM23
Recommended Position Specific Matrix for ECM23 comes from Badis et. al.

ECM23: Non-essential protein of unconfirmed function; affects pre-rRNA processing, may act as a negative regulator of the transcription of genes involved in pseudohyphal growth; homologous to Srd1p
Aliases: YPL021W, SRD2
For More information on ECM23 visit SGD
EDS1
Recommended Position Specific Matrix for EDS1 comes from Badis et. al.

EDS1: Putative zinc cluster protein; YBR033W is not an essential gene
Aliases: YBR033W
For More information on EDS1 visit SGD
ERT1
Recommended Position Specific Matrix for ERT1 comes from Aligned Matrix

ERT1: Transcriptional regulator of nonfermentable carbon utilization; GFP-fusion protein localizes to cytoplasm, nucleus; null mutation affects periodicity of transcriptional and metabolic oscillation; plays role in restricting Ty1 transposition
Aliases: YBR239C
For More information on ERT1 visit SGD
FHL1
Recommended Position Specific Matrix for FHL1 comes from Zhu et. al.

FHL1: Regulator of ribosomal protein transcription; has forkhead associated domain that binds phosphorylated proteins; also has forkhead DNA-binding domain but does not bind DNA in vitro; suppresses RNA pol III and splicing factor prp4 mutants
Aliases: YPR104C, SPP42
For More information on FHL1 visit SGD
FKH1
Recommended Position Specific Matrix for FKH1 comes from Foat et. al.

FKH1: Forkhead family transcription factor with a minor role in the expression of G2/M phase genes; negatively regulates transcriptional elongation; positive role in chromatin silencing at HML and HMR; regulates donor preference during switching
Aliases: YIL131C
For More information on FKH1 visit SGD
FKH2
Recommended Position Specific Matrix for FKH2 comes from Badis et. al.

FKH2: Forkhead family transcription factor with a major role in the expression of G2/M phase genes; positively regulates transcriptional elongation; negative role in chromatin silencing at HML and HMR; substrate of the Cdc28p/Clb5p kinase
Aliases: YNL068C
For More information on FKH2 visit SGD
FZF1
Recommended Position Specific Matrix for FZF1 comes from Badis et. al.

FZF1: Transcription factor involved in sulfite metabolism, sole identified regulatory target is SSU1, overexpression suppresses sulfite-sensitivity of many unrelated mutants due to hyperactivation of SSU1, contains five zinc fingers
Aliases: YGL254W, SUL1, RSU1, NRC299
For More information on FZF1 visit SGD
GAL4
Recommended Position Specific Matrix for GAL4 comes from Macisaac et. al

GAL4: DNA-binding transcription factor required for the activation of the GAL genes in response to galactose; repressed by Gal80p and activated by Gal3p
Aliases: YPL248C, GAL81
For More information on GAL4 visit SGD
GAL80
Recommended Position Specific Matrix for GAL80 comes from Pachkov et al

GAL80: Transcriptional regulator involved in the repression of GAL genes in the absence of galactose; inhibits transcriptional activation by Gal4p; inhibition relieved by Gal3p or Gal1p binding
Aliases: YML051W
For More information on GAL80 visit SGD
GAT1
Recommended Position Specific Matrix for GAT1 comes from Zhu et. al.

GAT1: Transcriptional activator of genes involved in nitrogen catabolite repression; contains a GATA-1-type zinc finger DNA-binding motif; activity and localization regulated by nitrogen limitation and Ure2p
Aliases: YFL021W, MEP80, NIL1
For More information on GAT1 visit SGD
GAT3
Recommended Position Specific Matrix for GAT3 comes from Macisaac et. al

GAT3: Protein containing GATA family zinc finger motifs
Aliases: YLR013W
For More information on GAT3 visit SGD
GAT4
Recommended Position Specific Matrix for GAT4 comes from Zhu et. al.

GAT4: Protein containing GATA family zinc finger motifs
Aliases: YIR013C
For More information on GAT4 visit SGD
GCN4
Recommended Position Specific Matrix for GCN4 comes from Aligned Matrix

GCN4: Basic leucine zipper (bZIP) transcriptional activator of amino acid biosynthetic genes in response to amino acid starvation; expression is tightly regulated at both the transcriptional and translational levels
Aliases: YEL009C, AAS101, ARG9, AAS3
For More information on GCN4 visit SGD
GCR1
Recommended Position Specific Matrix for GCR1 comes from Aligned Matrix

GCR1: Transcriptional activator of genes involved in glycolysis; DNA-binding protein that interacts and functions with the transcriptional activator Gcr2p
Aliases: YPL075W, LPF10
For More information on GCR1 visit SGD
GCR2
Recommended Position Specific Matrix for GCR2 comes from Macisaac et. al

GCR2: Transcriptional activator of genes involved in glycolysis; interacts and functions with the DNA-binding protein Gcr1p
Aliases: YNL199C
For More information on GCR2 visit SGD
GIS1
Recommended Position Specific Matrix for GIS1 comes from Badis et. al.

GIS1: JmjC domain-containing histone demethylase; transcription factor involved in expression of genes during nutrient limitation and in negative regulation of DPP1 and PHR1; activity is modulated by limited proteasome-mediated proteolysis
Aliases: YDR096W
For More information on GIS1 visit SGD
GLN3
Recommended Position Specific Matrix for GLN3 comes from Harbison et. al.

GLN3: Transcriptional activator of genes regulated by nitrogen catabolite repression (NCR), localization and activity regulated by quality of nitrogen source
Aliases: YER040W
For More information on GLN3 visit SGD
GSM1
Recommended Position Specific Matrix for GSM1 comes from Badis et. al.

GSM1: Putative zinc cluster protein of unknown function; proposed to be involved in the regulation of energy metabolism, based on patterns of expression and sequence analysis
Aliases: YJL103C
For More information on GSM1 visit SGD
GTS1
Recommended Position Specific Matrix for GTS1 comes from Macisaac et. al

GTS1: Arf3p GTPase Activating Protein (GAP) that localizes to endocytic patches; gts1 mutations affect budding, cell size, heat tolerance, sporulation, life span, ultradian rhythms; localizes to nucleus and induces flocculation when overexpressed
Aliases: YGL181W, LSR1, FHT1
For More information on GTS1 visit SGD
GZF3
Recommended Position Specific Matrix for GZF3 comes from Badis et. al.

GZF3: GATA zinc finger protein and Dal80p homolog that negatively regulates nitrogen catabolic gene expression by competing with Gat1p for GATA site binding; function requires a repressive carbon source; dimerizes with Dal80p and binds to Tor1p
Aliases: YJL110C, NIL2, DEH1
For More information on GZF3 visit SGD
HAC1
Recommended Position Specific Matrix for HAC1 comes from Macisaac et. al

HAC1: Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) that regulates the unfolded protein response, via UPRE binding, and membrane biogenesis; ER stress-induced splicing pathway facilitates efficient Hac1p synthesis
Aliases: YFL031W, IRE15, ERN4
For More information on HAC1 visit SGD
HAL9
Recommended Position Specific Matrix for HAL9 comes from Zhu et. al.

HAL9: Putative transcription factor containing a zinc finger; overexpression increases salt tolerance through increased expression of the ENA1 (Na+/Li+ extrusion pump) gene while gene disruption decreases both salt tolerance and ENA1 expression
Aliases: YOL089C
For More information on HAL9 visit SGD
HAP1
Recommended Position Specific Matrix for HAP1 comes from Aligned Matrix

HAP1: Zinc finger transcription factor involved in the complex regulation of gene expression in response to levels of heme and oxygen; the S288C sequence differs from other strain backgrounds due to a Ty1 insertion in the carboxy terminus
Aliases: YLR256W, CYP1
For More information on HAP1 visit SGD
HAP2
Recommended Position Specific Matrix for HAP2 comes from Macisaac et. al

HAP2: Subunit of the heme-activated, glucose-repressed Hap2p/3p/4p/5p CCAAT-binding complex, a transcriptional activator and global regulator of respiratory gene expression; contains sequences sufficient for both complex assembly and DNA binding
Aliases: YGL237C
For More information on HAP2 visit SGD
HAP3
Recommended Position Specific Matrix for HAP3 comes from Aligned Matrix

HAP3: Subunit of the heme-activated, glucose-repressed Hap2p/3p/4p/5p CCAAT-binding complex, a transcriptional activator and global regulator of respiratory gene expression; contains sequences contributing to both complex assembly and DNA binding
Aliases: YBL021C
For More information on HAP3 visit SGD
HAP4
Recommended Position Specific Matrix for HAP4 comes from Harbison et. al.

HAP4: Subunit of the heme-activated, glucose-repressed Hap2p/3p/4p/5p CCAAT-binding complex, a transcriptional activator and global regulator of respiratory gene expression; provides the principal activation function of the complex
Aliases: YKL109W
For More information on HAP4 visit SGD
HAP5
Recommended Position Specific Matrix for HAP5 comes from Pachkov et al

HAP5: Subunit of the heme-activated, glucose-repressed Hap2/3/4/5 CCAAT-binding complex, a transcriptional activator and global regulator of respiratory gene expression; required for assembly and DNA binding activity of the complex
Aliases: YOR358W
For More information on HAP5 visit SGD
HCM1
Recommended Position Specific Matrix for HCM1 comes from Badis et. al.

HCM1: Forkhead transcription factor that drives S-phase specific expression of genes involved in chromosome segregation, spindle dynamics, and budding; suppressor of calmodulin mutants with specific SPB assembly defects; telomere maintenance role
Aliases: YCR065W
For More information on HCM1 visit SGD
HMRA2
Recommended Position Specific Matrix for HMRA2 comes from Badis et. al.

HMRA2: Silenced copy of a2 at HMR; similarity to Alpha2p; required along with a1p for inhibiting expression of the HO endonuclease in a/alpha HO/HO diploid cells with an active mating-type interconversion system
Aliases: YCR096C, A2
For More information on HMRA2 visit SGD
HMS1
Recommended Position Specific Matrix for HMS1 comes from Morozov et. al.

HMS1: Basic helix-loop-helix (bHLH) protein with similarity to myc-family transcription factors; overexpression confers hyperfilamentous growth and suppresses the pseudohyphal filamentation defect of a diploid mep1 mep2 homozygous null mutant
Aliases: YOR032C
For More information on HMS1 visit SGD
HSF1
Recommended Position Specific Matrix for HSF1 comes from Pachkov et al

HSF1: Trimeric heat shock transcription factor, activates multiple genes in response to stresses that include hyperthermia; recognizes variable heat shock elements (HSEs) consisting of inverted NGAAN repeats; posttranslationally regulated
Aliases: YGL073W, MAS3, EXA3
For More information on HSF1 visit SGD
IME1
Recommended Position Specific Matrix for IME1 comes from Macisaac et. al

IME1: Master regulator of meiosis that is active only during meiotic events, activates transcription of early meiotic genes through interaction with Ume6p, degraded by the 26S proteasome following phosphorylation by Ime2p
Aliases: YJR094C
For More information on IME1 visit SGD
INO2
Recommended Position Specific Matrix for INO2 comes from Morozov et. al.

INO2: Component of the heteromeric Ino2p/Ino4p basic helix-loop-helix transcription activator that binds inositol/choline-responsive elements (ICREs), required for derepression of phospholipid biosynthetic genes in response to inositol depletion
Aliases: YDR123C, SCS1, DIE1
For More information on INO2 visit SGD
INO4
Recommended Position Specific Matrix for INO4 comes from Pachkov et al

INO4: Transcription factor required for derepression of inositol-choline-regulated genes involved in phospholipid synthesis; forms a complex, with Ino2p, that binds the inositol-choline-responsive element through a basic helix-loop-helix domain
Aliases: YOL108C
For More information on INO4 visit SGD
IXR1
Recommended Position Specific Matrix for IXR1 comes from Macisaac et. al

IXR1: Protein that binds DNA containing intrastrand cross-links formed by cisplatin, contains two HMG (high mobility group box) domains, which confer the ability to bend cisplatin-modified DNA; mediates aerobic transcriptional repression of COX5b
Aliases: YKL032C, ORD1
For More information on IXR1 visit SGD
JHD1
Recommended Position Specific Matrix for JHD1 comes from Macisaac et. al

JHD1: JmjC domain family histone demethylase specific for H3-K36, similar to proteins found in human, mouse, drosophila, X. laevis, C. elegans, and S. pombe
Aliases: YER051W, KDM2, JHDM1
For More information on JHD1 visit SGD
LEU3
Recommended Position Specific Matrix for LEU3 comes from Aligned Matrix

LEU3: Zinc-finger transcription factor that regulates genes involved in branched chain amino acid biosynthesis and ammonia assimilation; positively regulated by alpha-isopropylmalate, an intermediate in leucine biosynthesis
Aliases: YLR451W
For More information on LEU3 visit SGD
LYS14
Recommended Position Specific Matrix for LYS14 comes from Zhu et. al.

LYS14: Transcriptional activator involved in regulation of genes of the lysine biosynthesis pathway; requires 2-aminoadipate semialdehyde as co-inducer
Aliases: YDR034C
For More information on LYS14 visit SGD
MAC1
Recommended Position Specific Matrix for MAC1 comes from Aligned Matrix

MAC1: Copper-sensing transcription factor involved in regulation of genes required for high affinity copper transport
Aliases: YMR021C, CUA1
For More information on MAC1 visit SGD
MATA1
Recommended Position Specific Matrix for MATA1 comes from Macisaac et. al

MATA1: Expressed copy (at MATa) of a1; homeobox-domain protein that, along with alpha2, represses transcription of haploid-specific genes in diploid cells; a1 sequence is not present in SGD because the sequenced S288C strain is MATalpha, not MATa
Aliases: MATA1, A1
For More information on MATA1 visit SGD
MATA2
Recommended Position Specific Matrix for MATA2 comes from Fordyce et. al.

MATA2: Protein of unknown function, identical to the C-terminal 119 amino acid residues of the MATalpha2 protein; a2 sequence is not present in SGD because the sequenced S288C strain is MATalpha, not MATa
Aliases: MATA2, A2
For More information on MATA2 visit SGD
MATALPHA2
Recommended Position Specific Matrix for MATALPHA2 comes from Pachkov et al

MATALPHA2: Homeobox-domain protein that, with Mcm1p, represses a-specific genes in haploids; acts with A1p to repress transcription of haploid-specific genes in diploids; one of two genes encoded by the MATalpha mating type cassette
Aliases: YCR039C, ALPHA2
For More information on MATALPHA2 visit SGD
MBP1
Recommended Position Specific Matrix for MBP1 comes from Aligned Matrix

MBP1: Transcription factor involved in regulation of cell cycle progression from G1 to S phase, forms a complex with Swi6p that binds to MluI cell cycle box regulatory element in promoters of DNA synthesis genes
Aliases: YDL056W
For More information on MBP1 visit SGD
MCM1
Recommended Position Specific Matrix for MCM1 comes from Morozov et. al.

MCM1: Transcription factor involved in cell-type-specific transcription and pheromone response; plays a central role in the formation of both repressor and activator complexes
Aliases: YMR043W, FUN80
For More information on MCM1 visit SGD
MET28
Recommended Position Specific Matrix for MET28 comes from Morozov et. al.

MET28: Basic leucine zipper (bZIP) transcriptional activator in the Cbf1p-Met4p-Met28p complex, participates in the regulation of sulfur metabolism
Aliases: YIR017C
For More information on MET28 visit SGD
MET31
Recommended Position Specific Matrix for MET31 comes from Aligned Matrix

MET31: Zinc-finger DNA-binding protein, involved in transcriptional regulation of the methionine biosynthetic genes, similar to Met32p
Aliases: YPL038W
For More information on MET31 visit SGD
MET32
Recommended Position Specific Matrix for MET32 comes from Macisaac et. al

MET32: Zinc-finger DNA-binding protein, involved in transcriptional regulation of the methionine biosynthetic genes, similar to Met31p
Aliases: YDR253C
For More information on MET32 visit SGD
MET4
Recommended Position Specific Matrix for MET4 comes from Harbison et. al.

MET4: Leucine-zipper transcriptional activator, responsible for the regulation of the sulfur amino acid pathway, requires different combinations of the auxiliary factors Cbf1p, Met28p, Met31p and Met32p
Aliases: YNL103W
For More information on MET4 visit SGD
MGA1
Recommended Position Specific Matrix for MGA1 comes from Morozov et. al.

MGA1: Protein similar to heat shock transcription factor; multicopy suppressor of pseudohyphal growth defects of ammonium permease mutants
Aliases: YGR249W
For More information on MGA1 visit SGD
MIG1
Recommended Position Specific Matrix for MIG1 comes from Foat et. al.

MIG1: Transcription factor involved in glucose repression; sequence specific DNA binding protein containing two Cys2His2 zinc finger motifs; regulated by the SNF1 kinase and the GLC7 phosphatase
Aliases: YGL035C, TDS22, SSN1, CAT4
For More information on MIG1 visit SGD
MIG2
Recommended Position Specific Matrix for MIG2 comes from Zhu et. al.

MIG2: Protein containing zinc fingers, involved in repression, along with Mig1p, of SUC2 (invertase) expression by high levels of glucose; binds to Mig1p-binding sites in SUC2 promoter
Aliases: YGL209W, MLZ1
For More information on MIG2 visit SGD
MIG3
Recommended Position Specific Matrix for MIG3 comes from Zhu et. al.

MIG3: Probable transcriptional repressor involved in response to toxic agents such as hydroxyurea that inhibit ribonucleotide reductase; phosphorylation by Snf1p or the Mec1p pathway inactivates Mig3p, allowing induction of damage response genes
Aliases: YER028C
For More information on MIG3 visit SGD
MOT2
Recommended Position Specific Matrix for MOT2 comes from Harbison et. al.

MOT2: Subunit of the CCR4-NOT complex, which has roles in transcription regulation, mRNA degradation, and post-transcriptional modifications; with Ubc4p, ubiquitinates nascent polypeptide-associated complex subunits and histone demethyase Jhd2p
Aliases: YER068W, SIG1, NOT4
For More information on MOT2 visit SGD
MOT3
Recommended Position Specific Matrix for MOT3 comes from Macisaac et. al

MOT3: Nuclear transcription factor with two Cys2-His2 zinc fingers; involved in repression of a subset of hypoxic genes by Rox1p, repression of several DAN/TIR genes during aerobic growth, and repression of ergosterol biosynthetic genes
Aliases: YMR070W, ROX7
For More information on MOT3 visit SGD
MSN1
Recommended Position Specific Matrix for MSN1 comes from Fordyce et. al.

MSN1: Transcriptional activator involved in regulation of invertase and glucoamylase expression, invasive growth and pseudohyphal differentiation, iron uptake, chromium accumulation, and response to osmotic stress; localizes to the nucleus
Aliases: YOL116W, PHD2, MSS10, HRB382, FUP1
For More information on MSN1 visit SGD
MSN2
Recommended Position Specific Matrix for MSN2 comes from Harbison et. al.

MSN2: Transcriptional activator related to Msn4p; activated in stress conditions, which results in translocation from the cytoplasm to the nucleus; binds DNA at stress response elements of responsive genes, inducing gene expression
Aliases: YMR037C
For More information on MSN2 visit SGD
MSN4
Recommended Position Specific Matrix for MSN4 comes from Harbison et. al.

MSN4: Transcriptional activator related to Msn2p; activated in stress conditions, which results in translocation from the cytoplasm to the nucleus; binds DNA at stress response elements of responsive genes, inducing gene expression
Aliases: YKL062W
For More information on MSN4 visit SGD
NDD1
Recommended Position Specific Matrix for NDD1 comes from Harbison et. al.

NDD1: Transcriptional activator essential for nuclear division; localized to the nucleus; essential component of the mechanism that activates the expression of a set of late-S-phase-specific genes
Aliases: YOR372C
For More information on NDD1 visit SGD
NDT80
Recommended Position Specific Matrix for NDT80 comes from Zhu et. al.

NDT80: Meiosis-specific transcription factor required for exit from pachytene and for full meiotic recombination; activates middle sporulation genes; competes with Sum1p for binding to promoters containing middle sporulation elements (MSE)
Aliases: YHR124W
For More information on NDT80 visit SGD
NHP10
Recommended Position Specific Matrix for NHP10 comes from Badis et. al.

NHP10: Protein related to mammalian high mobility group proteins; preferentially binds DNA ends, protecting them from exonucleatic cleavage; likely component of the chromatin-remodeling complex INO80 complex; proposed to be involved in DNA repair
Aliases: YDL002C, HMO2
For More information on NHP10 visit SGD
NHP6A
Recommended Position Specific Matrix for NHP6A comes from Zhu et. al.

NHP6A: High-mobility group (HMG) protein that binds to and remodels nucleosomes; involved in recruiting FACT and other chromatin remodelling complexes to the chromosomes; functionally redundant with Nhp6Bp; homologous to mammalian HMGB1 and HMGB2
Aliases: YPR052C
For More information on NHP6A visit SGD
NHP6B
Recommended Position Specific Matrix for NHP6B comes from Zhu et. al.

NHP6B: High-mobility group (HMG) protein that binds to and remodels nucleosomes; involved in recruiting FACT and other chromatin remodelling complexes to the chromosomes; functionally redundant with Nhp6Ap; homologous to mammalian HMGB1 and HMGB2
Aliases: YBR089C-A, YBR090C-A
For More information on NHP6B visit SGD
NRG1
Recommended Position Specific Matrix for NRG1 comes from Aligned Matrix

NRG1: Transcriptional repressor that recruits the Cyc8p-Tup1p complex to promoters; mediates glucose repression and negatively regulates a variety of processes including filamentous growth and alkaline pH response
Aliases: YDR043C
For More information on NRG1 visit SGD
NRG2
Recommended Position Specific Matrix for NRG2 comes from Fordyce et. al.

NRG2: Transcriptional repressor that mediates glucose repression and negatively regulates filamentous growth; has similarity to Nrg1p
Aliases: YBR066C
For More information on NRG2 visit SGD
OAF1
Recommended Position Specific Matrix for OAF1 comes from Zhu et. al.

OAF1: Oleate-activated transcription factor, acts alone and as a heterodimer with Pip2p; activates genes involved in beta-oxidation of fatty acids and peroxisome organization and biogenesis
Aliases: YAL051W, YAF1
For More information on OAF1 visit SGD
OPI1
Recommended Position Specific Matrix for OPI1 comes from Foat et. al.

OPI1: Transcriptional regulator of a variety of genes; phosphorylation by protein kinase A stimulates Opi1p function in negative regulation of phospholipid biosynthetic genes; involved in telomere maintenance
Aliases: YHL020C
For More information on OPI1 visit SGD
ORC1
Recommended Position Specific Matrix for ORC1 comes from Pachkov et al

ORC1: Largest subunit of the origin recognition complex, which directs DNA replication by binding to replication origins and is also involved in transcriptional silencing; exhibits ATPase activity
Aliases: YML065W
For More information on ORC1 visit SGD
PDR1
Recommended Position Specific Matrix for PDR1 comes from Macisaac et. al

PDR1: Zinc cluster protein that is a master regulator involved in recruiting other zinc cluster proteins to pleiotropic drug response elements (PDREs) to fine tune the regulation of multidrug resistance genes
Aliases: YGL013C, TPE3, TPE1, TIL1, SMR2, NRA2, CYH3, BOR2, ANT1, AMY1
For More information on PDR1 visit SGD
PDR3
Recommended Position Specific Matrix for PDR3 comes from Morozov et. al.

PDR3: Transcriptional activator of the pleiotropic drug resistance network, regulates expression of ATP-binding cassette (ABC) transporters through binding to cis-acting sites known as PDREs (PDR responsive elements)
Aliases: YBL005W, TPE2, AMY2
For More information on PDR3 visit SGD
PDR8
Recommended Position Specific Matrix for PDR8 comes from Badis et. al.

PDR8: Transcription factor; targets include ATP-binding cassette (ABC) transporters, major facilitator superfamily transporters, and other genes involved in the pleiotropic drug resistance (PDR) phenomenon
Aliases: YLR266C
For More information on PDR8 visit SGD
PHD1
Recommended Position Specific Matrix for PHD1 comes from Aligned Matrix

PHD1: Transcriptional activator that enhances pseudohyphal growth; regulates expression of FLO11, an adhesin required for pseudohyphal filament formation; similar to StuA, an A. nidulans developmental regulator; potential Cdc28p substrate
Aliases: YKL043W
For More information on PHD1 visit SGD
PHO2
Recommended Position Specific Matrix for PHO2 comes from Zhu et. al.

PHO2: Homeobox transcription factor; regulatory targets include genes involved in phosphate metabolism; binds cooperatively with Pho4p to the PHO5 promoter; phosphorylation of Pho2p facilitates interaction with Pho4p
Aliases: YDL106C, phoB, GRF10, BAS2
For More information on PHO2 visit SGD
PHO4
Recommended Position Specific Matrix for PHO4 comes from Morozov et. al.

PHO4: Basic helix-loop-helix (bHLH) transcription factor of the myc-family; binds cooperatively with Pho2p to the PHO5 promoter; function is regulated by phosphorylation at multiple sites and by phosphate availability
Aliases: YFR034C, phoD
For More information on PHO4 visit SGD
PIP2
Recommended Position Specific Matrix for PIP2 comes from Foat et. al.

PIP2: Autoregulatory oleate-specific transcriptional activator of peroxisome proliferation, contains Zn(2)-Cys(6) cluster domain, forms heterodimer with Oaf1p, binds oleate response elements (OREs), activates beta-oxidation genes
Aliases: YOR363C, OAF2
For More information on PIP2 visit SGD
PPR1
Recommended Position Specific Matrix for PPR1 comes from Foat et. al.

PPR1: Zinc finger transcription factor containing a Zn(2)-Cys(6) binuclear cluster domain, positively regulates transcription of genes involved in uracil biosynthesis; activity may be modulated by interaction with Tup1p
Aliases: YLR014C
For More information on PPR1 visit SGD
PUT3
Recommended Position Specific Matrix for PUT3 comes from Morozov et. al.

PUT3: Transcriptional activator of proline utilization genes, constitutively binds PUT1 and PUT2 promoter sequences and undergoes a conformational change to form the active state; has a Zn(2)-Cys(6) binuclear cluster domain
Aliases: YKL015W
For More information on PUT3 visit SGD
RAP1
Recommended Position Specific Matrix for RAP1 comes from Morozov et. al.

RAP1: DNA-binding protein involved in either activation or repression of transcription, depending on binding site context; also binds telomere sequences and plays a role in telomeric position effect (silencing) and telomere structure
Aliases: YNL216W, TUF1, TBA1, GRF1
For More information on RAP1 visit SGD
RDR1
Recommended Position Specific Matrix for RDR1 comes from Zhu et. al.

RDR1: Transcriptional repressor involved in the control of multidrug resistance; negatively regulates expression of the PDR5 gene; member of the Gal4p family of zinc cluster proteins
Aliases: YOR380W
For More information on RDR1 visit SGD
RDS1
Recommended Position Specific Matrix for RDS1 comes from Zhu et. al.

RDS1: Zinc cluster transcription factor involved in conferring resistance to cycloheximide
Aliases: YCR106W
For More information on RDS1 visit SGD
RDS2
Recommended Position Specific Matrix for RDS2 comes from Zhao and Stormo

RDS2: Zinc cluster transcriptional activator involved in conferring resistance to ketoconazole
Aliases: YPL133C
For More information on RDS2 visit SGD
REB1
Recommended Position Specific Matrix for REB1 comes from Badis et. al.

REB1: RNA polymerase I enhancer binding protein; DNA binding protein which binds to genes transcribed by both RNA polymerase I and RNA polymerase II; required for termination of RNA polymerase I transcription
Aliases: YBR049C, GRF2
For More information on REB1 visit SGD
REI1
Recommended Position Specific Matrix for REI1 comes from Badis et. al.

REI1: Cytoplasmic pre-60S factor; required for the correct recycling of shuttling factors Alb1, Arx1 and Tif6 at the end of the ribosomal large subunit biogenesis; involved in bud growth in the mitotic signaling network
Aliases: YBR267W
For More information on REI1 visit SGD
RFX1
Recommended Position Specific Matrix for RFX1 comes from Macisaac et. al

RFX1: Major transcriptional repressor of DNA-damage-regulated genes, recruits repressors Tup1p and Cyc8p to their promoters; involved in DNA damage and replication checkpoint pathway; similar to a family of mammalian DNA binding RFX1-4 proteins
Aliases: YLR176C, CRT1
For More information on RFX1 visit SGD
RGM1
Recommended Position Specific Matrix for RGM1 comes from Foat et. al.

RGM1: Putative transcriptional repressor with proline-rich zinc fingers; overproduction impairs cell growth
Aliases: YMR182C
For More information on RGM1 visit SGD
RGT1
Recommended Position Specific Matrix for RGT1 comes from Macisaac et. al

RGT1: Glucose-responsive transcription factor that regulates expression of several glucose transporter (HXT) genes in response to glucose; binds to promoters and acts both as a transcriptional activator and repressor
Aliases: YKL038W
For More information on RGT1 visit SGD
RIM101
Recommended Position Specific Matrix for RIM101 comes from Harbison et. al.

RIM101: Transcriptional repressor involved in response to pH and in cell wall construction; required for alkaline pH-stimulated haploid invasive growth and sporulation; activated by proteolytic processing; similar to A. nidulans PacC
Aliases: YHL027W, RIM1
For More information on RIM101 visit SGD
RLM1
Recommended Position Specific Matrix for RLM1 comes from Aligned Matrix

RLM1: MADS-box transcription factor, component of the protein kinase C-mediated MAP kinase pathway involved in the maintenance of cell integrity; phosphorylated and activated by the MAP-kinase Slt2p
Aliases: YPL089C
For More information on RLM1 visit SGD
RME1
Recommended Position Specific Matrix for RME1 comes from Macisaac et. al

RME1: Zinc finger protein involved in control of meiosis; prevents meiosis by repressing IME1 expression and promotes mitosis by activating CLN2 expression; directly repressed by a1-alpha2 regulator; mediates cell type control of sporulation
Aliases: YGR044C, CSP1
For More information on RME1 visit SGD
ROX1
Recommended Position Specific Matrix for ROX1 comes from Fordyce et. al.

ROX1: Heme-dependent repressor of hypoxic genes; contains an HMG domain that is responsible for DNA bending activity
Aliases: YPR065W, REO1
For More information on ROX1 visit SGD
RPH1
Recommended Position Specific Matrix for RPH1 comes from Aligned Matrix

RPH1: JmjC domain-containing histone demethylase which can specifically demethylate H3K36 tri- and dimethyl modification states; transcriptional repressor of PHR1; Rph1p phosphorylation during DNA damage is under control of the MEC1-RAD53 pathway
Aliases: YER169W, KDM4
For More information on RPH1 visit SGD
RPN4
Recommended Position Specific Matrix for RPN4 comes from Aligned Matrix

RPN4: Transcription factor that stimulates expression of proteasome genes; Rpn4p levels are in turn regulated by the 26S proteasome in a negative feedback control mechanism; RPN4 is transcriptionally regulated by various stress responses
Aliases: YDL020C, UFD5, SON1
For More information on RPN4 visit SGD
RSC3
Recommended Position Specific Matrix for RSC3 comes from Badis et. al.

RSC3: Component of the RSC chromatin remodeling complex; essential gene required for maintenance of proper ploidy and regulation of ribosomal protein genes and the cell wall/stress response; highly similar to Rsc30p
Aliases: YDR303C
For More information on RSC3 visit SGD
RSC30
Recommended Position Specific Matrix for RSC30 comes from Badis et. al.

RSC30: Component of the RSC chromatin remodeling complex; non-essential gene required for regulation of ribosomal protein genes and the cell wall/stress response; highly similar to Rsc3p; null mutants are osmosensitive
Aliases: YHR056C
For More information on RSC30 visit SGD
RSF2
Recommended Position Specific Matrix for RSF2 comes from Badis et. al.

RSF2: Zinc-finger protein involved in transcriptional control of both nuclear and mitochondrial genes, many of which specify products required for glycerol-based growth, respiration, and other functions
Aliases: YJR127C, ZMS1
For More information on RSF2 visit SGD
RTG1
Recommended Position Specific Matrix for RTG1 comes from Foat et. al.

RTG1: Transcription factor (bHLH) involved in interorganelle communication between mitochondria, peroxisomes, and nucleus
Aliases: YOL067C
For More information on RTG1 visit SGD
RTG3
Recommended Position Specific Matrix for RTG3 comes from Macisaac et. al

RTG3: Basic helix-loop-helix-leucine zipper (bHLH/Zip) transcription factor that forms a complex with another bHLH/Zip protein, Rtg1p, to activate the retrograde (RTG) and TOR pathways
Aliases: YBL103C
For More information on RTG3 visit SGD
SFL1
Recommended Position Specific Matrix for SFL1 comes from Zhu et. al.

SFL1: Transcriptional repressor and activator; involved in repression of flocculation-related genes, and activation of stress responsive genes; negatively regulated by cAMP-dependent protein kinase A subunit Tpk2p
Aliases: YOR140W
For More information on SFL1 visit SGD
SFP1
Recommended Position Specific Matrix for SFP1 comes from Zhu et. al.

SFP1: Transcription factor that controls expression of ribosome biogenesis genes in response to nutrients and stress, regulates G2/M transitions during mitotic cell cycle and DNA-damage response, modulates cell size; regulated by TORC1 and Mrs6p
Aliases: YLR403W
For More information on SFP1 visit SGD
SIP4
Recommended Position Specific Matrix for SIP4 comes from Aligned Matrix

SIP4: C6 zinc cluster transcriptional activator that binds to the carbon source-responsive element (CSRE) of gluconeogenic genes; involved in the positive regulation of gluconeogenesis; regulated by Snf1p protein kinase; localized to the nucleus
Aliases: YJL089W
For More information on SIP4 visit SGD
SKN7
Recommended Position Specific Matrix for SKN7 comes from Foat et. al.

SKN7: Nuclear response regulator and transcription factor, part of a branched two-component signaling system; required for optimal induction of heat-shock genes in response to oxidative stress; involved in osmoregulation
Aliases: YHR206W, POS9, BRY1
For More information on SKN7 visit SGD
SKO1
Recommended Position Specific Matrix for SKO1 comes from Macisaac et. al

SKO1: Basic leucine zipper (bZIP) transcription factor of the ATF/CREB family, forms a complex with Tup1p and Ssn6p to both activate and repress transcription; cytosolic and nuclear protein involved in osmotic and oxidative stress responses
Aliases: YNL167C, ACR1
For More information on SKO1 visit SGD
SMP1
Recommended Position Specific Matrix for SMP1 comes from Morozov et. al.

SMP1: Putative transcription factor involved in regulating the response to osmotic stress; member of the MADS-box family of transcription factors
Aliases: YBR182C
For More information on SMP1 visit SGD
SNF1
Recommended Position Specific Matrix for SNF1 comes from Macisaac et. al

SNF1: AMP-activated serine/threonine protein kinase found in a complex containing Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis
Aliases: YDR477W, PAS14, HAF3, GLC2, CCR1, CAT1
For More information on SNF1 visit SGD
SNT2
Recommended Position Specific Matrix for SNT2 comes from Macisaac et. al

SNT2: DNA binding protein with similarity to the S. pombe Snt2 protein; computational analysis suggests a role in regulation of expression of genes encoding amine transporters
Aliases: YGL131C
For More information on SNT2 visit SGD
SOK2
Recommended Position Specific Matrix for SOK2 comes from Harbison et. al.

SOK2: Nuclear protein that plays a regulatory role in the cyclic AMP (cAMP)-dependent protein kinase (PKA) signal transduction pathway; negatively regulates pseudohyphal differentiation; homologous to several transcription factors
Aliases: YMR016C
For More information on SOK2 visit SGD
SPT15
Recommended Position Specific Matrix for SPT15 comes from Pachkov et al

SPT15: TATA-binding protein, general transcription factor that interacts with other factors to form the preinitiation complex at promoters, essential for viability
Aliases: YER148W, TBP, TBP1, BTF1
For More information on SPT15 visit SGD
SPT2
Recommended Position Specific Matrix for SPT2 comes from Harbison et. al.

SPT2: Protein involved in negative regulation of transcription; required for RNA polyadenylation; exhibits regulated interactions with both histones and SWI-SNF components, has similarity to mammalian HMG1 proteins
Aliases: YER161C, EXA1, SIN1
For More information on SPT2 visit SGD
SPT23
Recommended Position Specific Matrix for SPT23 comes from Macisaac et. al

SPT23: ER membrane protein involved in regulation of OLE1 transcription, acts with homolog Mga2p; inactive ER form dimerizes and one subunit is then activated by ubiquitin/proteasome-dependent processing followed by nuclear targeting
Aliases: YKL020C
For More information on SPT23 visit SGD
SRD1
Recommended Position Specific Matrix for SRD1 comes from Zhu et. al.

SRD1: Protein involved in the processing of pre-rRNA to mature rRNA; contains a C2/C2 zinc finger motif; srd1 mutation suppresses defects caused by the rrp1-1 mutation
Aliases: YCR018C
For More information on SRD1 visit SGD
STB1
Recommended Position Specific Matrix for STB1 comes from Harbison et. al.

STB1: Protein with a role in regulation of MBF-specific transcription at Start, phosphorylated by Cln-Cdc28p kinases in vitro; unphosphorylated form binds Swi6p and binding is required for Stb1p function; expression is cell-cycle regulated
Aliases: YNL309W
For More information on STB1 visit SGD
STB2
Recommended Position Specific Matrix for STB2 comes from Macisaac et. al

STB2: Protein that interacts with Sin3p in a two-hybrid assay and is part of a large protein complex with Sin3p and Stb1p
Aliases: YMR053C
For More information on STB2 visit SGD
STB3
Recommended Position Specific Matrix for STB3 comes from Zhu et. al.

STB3: Ribosomal RNA processing element (RRPE)-binding protein involved in the glucose-induced transition from quiescence to growth; restricted to nucleus in quiescent cells, released into cytoplasm after glucose repletion; binds Sin3p
Aliases: YDR169C
For More information on STB3 visit SGD
STB4
Recommended Position Specific Matrix for STB4 comes from Pachkov et al

STB4: Protein that binds Sin3p in a two-hybrid assay; contains a Zn(II)2Cys6 zinc finger domain characteristic of DNA-binding proteins; computational analysis suggests a role in regulation of expression of genes encoding transporters
Aliases: YMR019W
For More information on STB4 visit SGD
STB5
Recommended Position Specific Matrix for STB5 comes from Harbison et. al.

STB5: Transcription factor, involved in regulating multidrug resistance and oxidative stress response; forms a heterodimer with Pdr1p; contains a Zn(II)2Cys6 zinc finger domain that interacts with a pleiotropic drug resistance element in vitro
Aliases: YHR178W
For More information on STB5 visit SGD
STE12
Recommended Position Specific Matrix for STE12 comes from Badis et. al.

STE12: Transcription factor that is activated by a MAP kinase signaling cascade, activates genes involved in mating or pseudohyphal/invasive growth pathways; cooperates with Tec1p transcription factor to regulate genes specific for invasive growth
Aliases: YHR084W
For More information on STE12 visit SGD
STP1
Recommended Position Specific Matrix for STP1 comes from Macisaac et. al

STP1: Transcription factor, undergoes proteolytic processing by SPS (Ssy1p-Ptr3p-Ssy5p)-sensor component Ssy5p in response to extracellular amino acids; activates transcription of amino acid permease genes and may have a role in tRNA processing
Aliases: YDR463W, SSY2, BAP1
For More information on STP1 visit SGD
STP2
Recommended Position Specific Matrix for STP2 comes from Zhu et. al.

STP2: Transcription factor, activated by proteolytic processing in response to signals from the SPS sensor system for external amino acids; activates transcription of amino acid permease genes
Aliases: YHR006W
For More information on STP2 visit SGD
STP3
Recommended Position Specific Matrix for STP3 comes from Badis et. al.

STP3: Zinc-finger protein of unknown function, possibly involved in pre-tRNA splicing and in uptake of branched-chain amino acids
Aliases: YLR375W
For More information on STP3 visit SGD
STP4
Recommended Position Specific Matrix for STP4 comes from Badis et. al.

STP4: Protein containing a Kruppel-type zinc-finger domain; has similarity to Stp1p, Stp2p, and Stp3p
Aliases: YDL048C
For More information on STP4 visit SGD
SUM1
Recommended Position Specific Matrix for SUM1 comes from Pachkov et al

SUM1: Transcriptional repressor required for mitotic repression of middle sporulation-specific genes; also acts as general replication initiation factor; involved in telomere maintenance, chromatin silencing; regulated by pachytene checkpoint
Aliases: YDR310C
For More information on SUM1 visit SGD
SUT1
Recommended Position Specific Matrix for SUT1 comes from Harbison et. al.

SUT1: Transcription factor of the Zn[II]2Cys6 family involved in sterol uptake; involved in induction of hypoxic gene expression
Aliases: YGL162W
For More information on SUT1 visit SGD
SUT2
Recommended Position Specific Matrix for SUT2 comes from Zhu et. al.

SUT2: Putative transcription factor; multicopy suppressor of mutations that cause low activity of the cAMP/protein kinase A pathway; highly similar to Sut1p
Aliases: YPR009W
For More information on SUT2 visit SGD
SWI4
Recommended Position Specific Matrix for SWI4 comes from Macisaac et. al

SWI4: DNA binding component of the SBF complex (Swi4p-Swi6p), a transcriptional activator that in concert with MBF (Mbp1-Swi6p) regulates late G1-specific transcription of targets including cyclins and genes required for DNA synthesis and repair
Aliases: YER111C, ART1
For More information on SWI4 visit SGD
SWI5
Recommended Position Specific Matrix for SWI5 comes from Badis et. al.

SWI5: Transcription factor that activates transcription of genes expressed at the M/G1 phase boundary and in G1 phase; localization to the nucleus occurs during G1 and appears to be regulated by phosphorylation by Cdc28p kinase
Aliases: YDR146C
For More information on SWI5 visit SGD
SWI6
Recommended Position Specific Matrix for SWI6 comes from Macisaac et. al

SWI6: Transcription cofactor, forms complexes with DNA-binding proteins Swi4p and Mbp1p to regulate transcription at the G1/S transition; involved in meiotic gene expression; localization regulated by phosphorylation; potential Cdc28p substrate
Aliases: YLR182W, SDS11, PSL8
For More information on SWI6 visit SGD
TBF1
Recommended Position Specific Matrix for TBF1 comes from Zhu et. al.

TBF1: Telobox-containing general regulatory factor; binds to TTAGGG repeats within subtelomeric anti-silencing regions (STARs) and possibly throughout the genome and mediates their insulating capacity by blocking silent chromatin propagation
Aliases: YPL128C, LPI16
For More information on TBF1 visit SGD
TBS1
Recommended Position Specific Matrix for TBS1 comes from Zhu et. al.

TBS1: Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
Aliases: YBR150C
For More information on TBS1 visit SGD
TEA1
Recommended Position Specific Matrix for TEA1 comes from Zhu et. al.

TEA1: Ty1 enhancer activator required for full levels of Ty enhancer-mediated transcription; C6 zinc cluster DNA-binding protein
Aliases: YOR337W
For More information on TEA1 visit SGD
TEC1
Recommended Position Specific Matrix for TEC1 comes from Aligned Matrix

TEC1: Transcription factor required for full Ty1 expression, Ty1-mediated gene activation, and haploid invasive and diploid pseudohyphal growth; TEA/ATTS DNA-binding domain family member
Aliases: YBR083W, ROC1
For More information on TEC1 visit SGD
THI2
Recommended Position Specific Matrix for THI2 comes from Macisaac et. al

THI2: Zinc finger protein of the Zn(II)2Cys6 type, probable transcriptional activator of thiamine biosynthetic genes
Aliases: YBR240C, phoF, PHO6
For More information on THI2 visit SGD
THO2
Recommended Position Specific Matrix for THO2 comes from Harbison et. al.

THO2: Subunit of the THO complex, which is required for efficient transcription elongation and involved in transcriptional elongation-associated recombination; required for LacZ RNA expression from certain plasmids
Aliases: YNL139C, RLR1, LDB5, ZRG13
For More information on THO2 visit SGD
TOD6
Recommended Position Specific Matrix for TOD6 comes from Zhu et. al.

TOD6: PAC motif binding protein involved in rRNA and ribosome biogenesis; subunit of the RPD3L histone deacetylase complex; Myb-like HTH transcription factor, similar to Dot6p; hypophosphorylated by rapamycin treatment in a Sch9p-dependent manne
Aliases: YBL054W, PBF1
For More information on TOD6 visit SGD
TOS8
Recommended Position Specific Matrix for TOS8 comes from Badis et. al.

TOS8: Homeodomain-containing protein and putative transcription factor found associated with chromatin; target of SBF transcription factor; induced during meiosis and under cell-damaging conditions; similar to Cup9p transcription factor
Aliases: YGL096W
For More information on TOS8 visit SGD
TYE7
Recommended Position Specific Matrix for TYE7 comes from Aligned Matrix

TYE7: Serine-rich protein that contains a basic-helix-loop-helix (bHLH) DNA binding motif; binds E-boxes of glycolytic genes and contributes to their activation; may function as a transcriptional activator in Ty1-mediated gene expression
Aliases: YOR344C, SGC1
For More information on TYE7 visit SGD
UGA3
Recommended Position Specific Matrix for UGA3 comes from Morozov et. al.

UGA3: Transcriptional activator necessary for gamma-aminobutyrate (GABA)-dependent induction of GABA genes (such as UGA1, UGA2, UGA4); zinc-finger transcription factor of the Zn(2)-Cys(6) binuclear cluster domain type; localized to the nucleus
Aliases: YDL170W
For More information on UGA3 visit SGD
UME1
Recommended Position Specific Matrix for UME1 comes from Harbison et. al.

UME1: Negative regulator of meiosis, required for repression of a subset of meiotic genes during vegetative growth, binding of histone deacetylase Rpd3p required for activity, contains a NEE box and a WD repeat motif; homologous with Wtm1p, Wtm2p
Aliases: YPL139C, WTM3
For More information on UME1 visit SGD
UME6
Recommended Position Specific Matrix for UME6 comes from Pachkov et al

UME6: Key transcriptional regulator of early meiotic genes, binds URS1 upstream regulatory sequence, couples metabolic responses to nutritional cues with initiation and progression of meiosis, forms complex with Ime1p, and also with Sin3p-Rpd3p
Aliases: YDR207C, RIM16, NIM2, CAR80
For More information on UME6 visit SGD
UPC2
Recommended Position Specific Matrix for UPC2 comes from Foat et. al.

UPC2: Sterol regulatory element binding protein, induces transcription of sterol biosynthetic genes and of DAN/TIR gene products; Ecm22p homolog; relocates from intracellular membranes to perinuclear foci on sterol depletion
Aliases: YDR213W, MOX4
For More information on UPC2 visit SGD
URC2
Recommended Position Specific Matrix for URC2 comes from Macisaac et. al

URC2: Putative Zn(II)2Cys6 motif containing transcription factor; non-essential gene identified in a screen for mutants with increased levels of rDNA transcription; similar to S. kluyveri Urc2p involved in uracil catabolism
Aliases: YDR520C, RRT4
For More information on URC2 visit SGD
USV1
Recommended Position Specific Matrix for USV1 comes from Badis et. al.

USV1: Putative transcription factor containing a C2H2 zinc finger; mutation affects transcriptional regulation of genes involved in growth on non-fermentable carbon sources, response to salt stress and cell wall biosynthesis
Aliases: YPL230W, NSF1
For More information on USV1 visit SGD
WAR1
Recommended Position Specific Matrix for WAR1 comes from Foat et. al.

WAR1: Homodimeric Zn2Cys6 zinc finger transcription factor; binds to a weak acid response element to induce transcription of PDR12 and FUN34, encoding an acid transporter and a putative ammonia transporter, respectively
Aliases: YML076C
For More information on WAR1 visit SGD
XBP1
Recommended Position Specific Matrix for XBP1 comes from Foat et. al.

XBP1: Transcriptional repressor that binds to promoter sequences of the cyclin genes, CYS3, and SMF2; expression is induced by stress or starvation during mitosis, and late in meiosis; member of the Swi4p/Mbp1p family; potential Cdc28p substrate
Aliases: YIL101C
For More information on XBP1 visit SGD
YAP1
Recommended Position Specific Matrix for YAP1 comes from Pachkov et al

YAP1: Basic leucine zipper (bZIP) transcription factor required for oxidative stress tolerance; activated by H2O2 through the multistep formation of disulfide bonds and transit from the cytoplasm to the nucleus; mediates resistance to cadmium
Aliases: YML007W, SNQ3, PAR1
For More information on YAP1 visit SGD
YAP3
Recommended Position Specific Matrix for YAP3 comes from Morozov et. al.

YAP3: Basic leucine zipper (bZIP) transcription factor
Aliases: YHL009C
For More information on YAP3 visit SGD
YAP5
Recommended Position Specific Matrix for YAP5 comes from Morozov et. al.

YAP5: Basic leucine zipper (bZIP) transcription factor
Aliases: YIR018W
For More information on YAP5 visit SGD
YAP6
Recommended Position Specific Matrix for YAP6 comes from Aligned Matrix

YAP6: Putative basic leucine zipper (bZIP) transcription factor; overexpression increases sodium and lithium tolerance; computational analysis suggests a role in regulation of expression of genes involved in carbohydrate metabolism
Aliases: YDR259C, HAL7
For More information on YAP6 visit SGD
YAP7
Recommended Position Specific Matrix for YAP7 comes from Aligned Matrix

YAP7: Putative basic leucine zipper (bZIP) transcription factor
Aliases: YOL028C
For More information on YAP7 visit SGD
YDR026C
Recommended Position Specific Matrix for YDR026C comes from Pachkov et al

YDR026C: Function Unknown
Aliases: No Aliases
For More information on YDR026C visit SGD
YER130C
Recommended Position Specific Matrix for YER130C comes from Badis et. al.

YER130C: Function Unknown
Aliases: No Aliases
For More information on YER130C visit SGD
YER184C
Recommended Position Specific Matrix for YER184C comes from Badis et. al.

YER184C: Function Unknown
Aliases: No Aliases
For More information on YER184C visit SGD
YGR067C
Recommended Position Specific Matrix for YGR067C comes from Zhao and Stormo

YGR067C: Function Unknown
Aliases: No Aliases
For More information on YGR067C visit SGD
YHP1
Recommended Position Specific Matrix for YHP1 comes from Macisaac et. al

YHP1: One of two homeobox transcriptional repressors (see also Yox1p), that bind to Mcm1p and to early cell cycle box (ECB) elements of cell cycle regulated genes, thereby restricting ECB-mediated transcription to the M/G1 interval
Aliases: YDR451C
For More information on YHP1 visit SGD
YKL222C
Recommended Position Specific Matrix for YKL222C comes from Zhu et. al.

YKL222C: Function Unknown
Aliases: No Aliases
For More information on YKL222C visit SGD
YLL054C
Recommended Position Specific Matrix for YLL054C comes from Zhu et. al.

YLL054C: Function Unknown
Aliases: No Aliases
For More information on YLL054C visit SGD
YLR278C
Recommended Position Specific Matrix for YLR278C comes from Badis et. al.

YLR278C: Function Unknown
Aliases: No Aliases
For More information on YLR278C visit SGD
YML081W
Recommended Position Specific Matrix for YML081W comes from Zhao and Stormo

YML081W: Function Unknown
Aliases: No Aliases
For More information on YML081W visit SGD
YNR063W
Recommended Position Specific Matrix for YNR063W comes from Badis et. al.

YNR063W: Function Unknown
Aliases: No Aliases
For More information on YNR063W visit SGD
YOX1
Recommended Position Specific Matrix for YOX1 comes from Badis et. al.

YOX1: Homeodomain-containing transcriptional repressor, binds to Mcm1p and to early cell cycle boxes (ECBs) in the promoters of cell cycle-regulated genes expressed in M/G1 phase; expression is cell cycle-regulated; potential Cdc28p substrate
Aliases: YML027W
For More information on YOX1 visit SGD
YPR013C
Recommended Position Specific Matrix for YPR013C comes from Zhu et. al.

YPR013C: Function Unknown
Aliases: No Aliases
For More information on YPR013C visit SGD
YPR015C
Recommended Position Specific Matrix for YPR015C comes from Zhu et. al.

YPR015C: Function Unknown
Aliases: No Aliases
For More information on YPR015C visit SGD
YPR022C
Recommended Position Specific Matrix for YPR022C comes from Badis et. al.

YPR022C: Function Unknown
Aliases: No Aliases
For More information on YPR022C visit SGD
YPR196W
Recommended Position Specific Matrix for YPR196W comes from Badis et. al.

YPR196W: Function Unknown
Aliases: No Aliases
For More information on YPR196W visit SGD
YRM1
Recommended Position Specific Matrix for YRM1 comes from Zhu et. al.

YRM1: Zn2-Cys6 zinc-finger transcription factor that activates genes involved in multidrug resistance; paralog of Yrr1p, acting on an overlapping set of target genes
Aliases: YOR172W
For More information on YRM1 visit SGD
YRR1
Recommended Position Specific Matrix for YRR1 comes from Macisaac et. al

YRR1: Zn2-Cys6 zinc-finger transcription factor that activates genes involved in multidrug resistance; paralog of Yrm1p, acting on an overlapping set of target genes
Aliases: YOR162C, PDR2
For More information on YRR1 visit SGD
ZAP1
Recommended Position Specific Matrix for ZAP1 comes from Harbison et. al.

ZAP1: Zinc-regulated transcription factor; binds to zinc-responsive promoters to induce transcription of certain genes in presence of zinc, represses other genes in low zinc; regulates its own transcription; contains seven zinc-finger domains
Aliases: YJL056C, ZRG10
For More information on ZAP1 visit SGD