ScerTF

ScerTF catalogs over 1,200 position weight matrices (PWMs) for 196 different yeast transcription factors. We've curated 11 literature sources, benchmarked the published position-specific scoring matrices against in-vivo TF occupancy data and TF deletion experiments, and combined the most accurate models to produce a single collection of the best performing weight matrices for Saccharomyces cerevisiae.

ScerTF is useful for a wide range of problems, such as linking regulatory sites with transcription factors, identifying a transcription factor based on a user-input matrix, finding the genes bound/regulated by a particular TF, and finding regulatory interactions between transcription factors.

Enter a TF name to find the recommended matrix for a particular TF, or enter a nucleotide sequence to identify all TFs that could bind a particular region

Search for a TF name or DNA sequence: [Load example Sequence]

DNA sequences are limited to 20 bases
Example Inputs: ABF1, GATAAG, ggctt
Paste a matrix below in consensus format to search for similar TFs: [Load example Matrix]

Consensus Matrix Format:
A | 0.515 0.030 0.064 0.687 0.044 0.117 0.382
C | 0.087 0.028 0.885 0.056 0.561 0.182 0.178
G | 0.317 0.045 0.024 0.190 0.024 0.164 0.138
T | 0.081 0.897 0.027 0.067 0.371 0.537 0.303